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kellylen
The Order of Denderah
Joined: 21 Nov 2006
Posts: 2823
Location: New Jersey
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 Posted: Wed Jul 11, 2007 9:17 pm Post subject: Spencer the solution! |
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Hey hun 
Here is the tentative solution to the papers you gave us today
| Quote: | The Bree Solution (that sounds REALLY important Shocked)
Objectives:
How to tansform Bree from TRAIT: POSITIVE to TRAIT:NEGATIVE
Given Facts:
1) Bree's blood contains a special Ribozyme mutated and unique only to her
2) The Gene for said ribozyme has a regulatory hyper mutation that changes with every generation
3) A non-functioning mutated ribozyme exists and manifests differently in every Hymn of One girl
4) This portion still functions but you cannot block it because the Complementary Strand of RNA won't copy
Theoretical Solution
1) Block the ribozyme in question by obtaining a sample of the that same ribozyme in order to copy it
2) Create a complementary strand of RNA
3) Q.E.D. strand will bind to ribozyme and occlude its copy
Practical Solution
1) obtain blood sample of Bree
2) synthesize complimentary strand of RNA
3) inject bree with this compliementary strand
4) Q.E.D. ribozymes blocked rendered ineffectual
Intended Results
1) Once synthesized and injected into bree she'll become trait negative
2) additional consequences (if any) - TBD
Bree Trait Reference Points
Theories concerning ribozyme function
a)RNAse P related -tRNA cleavage
b)splicosome related - intron/exon splicing
c)Hammerhead related - telomere synthesis
d)GlmS ribozyme related - fructose 6-phosphate pathway |
this is what we think so far. and most of it is 99% sure on
_________________
-Kelly
Last edited by kellylen on Wed Jul 11, 2007 9:52 pm; edited 2 times in total |
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Samara
Enthusiastic Fan
Joined: 30 Nov 2006
Posts: 356
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| Posted: Wed Jul 11, 2007 9:46 pm Post subject: |
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To be honst, I think this solution was posted in haste. For example:
That's not actually a word...
I believe that the word is "ineffectual" |
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kellylen
The Order of Denderah
Joined: 21 Nov 2006
Posts: 2823
Location: New Jersey
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| Posted: Wed Jul 11, 2007 9:49 pm Post subject: |
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fixed it. the point is that the foundation is there. the important parts are there. a word here or there will not... or well should not throw off the whole thing
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-Kelly |
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anniid
Lonely Fan
Joined: 08 Dec 2006
Posts: 241
Location: A snowflake
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| Posted: Wed Jul 11, 2007 9:49 pm Post subject: Look at us. we're so cool... |
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See!?
You should have posted that paper sooner... within 2-3 hours we had a solution. (It's correctness is um... relative...)
Alright. Check our solution and give us another puzzle!!!
Come on... you know you want to, Spencer.
_________________
One day you'll know who I am. On that day, so will everyone else.
Acting president of the Jonas is Sexy Fan Club!
Member of the Sarah Fan Club and the Daniel-Sarah Romance Promotion Force. |
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ohpete
Casual Observer
Joined: 11 Jul 2007
Posts: 40
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| Posted: Wed Jul 11, 2007 10:13 pm Post subject: |
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theres my copy. im too exauhsted to check it against yours for the moment kelly. ive got to get some food in me. but here it is as a back up.
The Bree Solution (that sounds REALLY important )
Objectives:
How to transform Bree from TRAIT: POSITIVE to TRAIT: NEGATIVE
Given Facts:
1) Bree's blood contains a special ribozyme mutated and unique only to her.
2) The gene for said ribozyme has a regulatory hyper mutation that changes with every generation.
3) A non-functioning mutated (?) ribozyme exists and manifests differently in every Hymn of One girl.
4) This portion still functions but you cannot block it because the complimentary strands of RNA won't copy.
Theoretical Solution
1) Block the ribozyme in question by obtaining a sample of that same ribozyme in order to copy it.
2) Create complimentary strand of RNA.
3) Q.E.D. strand will bind to ribozyme and occlude its copy.
Practical Solution
1) Obtain blood sample of Bree.
2) Synthesize complimentary strand of RNA
3) Inject Bree with this complementary strand.
4) Q.E.D. ribozymes blocked will be rendered ineffectual.
Intended Results
1) Once synthesized and injected into Bree she'll become trait negative
2) Additional consequences (if any) - TBD
Bree Trait Reference Points
The steps concerning ribozyme function
RNAse P related -tRNA cleavage
Splicosome related - intron/exon splicing
Hammerhead or Telomerase(?) related - telomere synthesis
GlmS ribozyme related - fructose 6-phosphate pathway |
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SivartAlappes
Lonely Fan
Joined: 02 Oct 2006
Posts: 209
Location: Virginia but moving to Cali soon
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| Posted: Wed Jul 11, 2007 10:14 pm Post subject: Re: Look at us. we're so cool... |
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| anniid wrote: | See!?
You should have posted that paper sooner... within 2-3 hours we had a solution. (It's correctness is um... relative...)
Alright. Check our solution and give us another puzzle!!!
Come on... you know you want to, Spencer. |
1 hour and 41 minutes, actually. |
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kellylen
The Order of Denderah
Joined: 21 Nov 2006
Posts: 2823
Location: New Jersey
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| Posted: Wed Jul 11, 2007 10:15 pm Post subject: Re: Look at us. we're so cool... |
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| SivartAlappes wrote: | | anniid wrote: | See!?
You should have posted that paper sooner... within 2-3 hours we had a solution. (It's correctness is um... relative...)
Alright. Check our solution and give us another puzzle!!!
Come on... you know you want to, Spencer. |
1 hour and 41 minutes, actually. |
actually i think its a lot less than that
_________________
-Kelly |
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emerrs11
Lonely Fan
Joined: 29 Dec 2006
Posts: 168
Location: In the cactus HQ
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| Posted: Wed Jul 11, 2007 10:17 pm Post subject: |
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I agree Kelly! I am 99.99% sure. I trust these answers as much as I trust Neutragena!
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"We're being chased by security!" ~Jonas. |
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SivartAlappes
Lonely Fan
Joined: 02 Oct 2006
Posts: 209
Location: Virginia but moving to Cali soon
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| Posted: Wed Jul 11, 2007 10:20 pm Post subject: Re: Look at us. we're so cool... |
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| kellylen wrote: | | SivartAlappes wrote: | | anniid wrote: | See!?
You should have posted that paper sooner... within 2-3 hours we had a solution. (It's correctness is um... relative...)
Alright. Check our solution and give us another puzzle!!!
Come on... you know you want to, Spencer. |
1 hour and 41 minutes, actually. |
actually i think its a lot less than that |
Well, the 1 hour and 41 minutes is the time between when Spencer posted the letter, and when you posted the solution. |
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Aponi
Devoted Fan
Joined: 26 Apr 2007
Posts: 545
Location: New York
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| Posted: Wed Jul 11, 2007 10:21 pm Post subject: Re: Look at us. we're so cool... |
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| kellylen wrote: | | SivartAlappes wrote: | | anniid wrote: | See!?
You should have posted that paper sooner... within 2-3 hours we had a solution. (It's correctness is um... relative...)
Alright. Check our solution and give us another puzzle!!!
Come on... you know you want to, Spencer. |
1 hour and 41 minutes, actually. |
actually i think its a lot less than that |
It was posted around 9:30, and by the time I was done with it enough to look at the clock it was around 11. Sounds about right to me
And I have to say, WTG US! Puzzle-solving ftw
Seriously, props to everyone who helped (Yes Kelly, even Travis XD)
_________________
The names Julie.
Bree and Jonas Forever! <3
Grand Master of Praise of the SSJF but Shhh about it 'k? XD
My LG15 Vid |
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QtheC
Enthusiastic Fan
Joined: 22 Feb 2007
Posts: 374
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| Posted: Wed Jul 11, 2007 10:35 pm Post subject: |
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| Quote: | | 3) Q.E.D. strand will bind to ribozyme and occlude its copy |
| Quote: | | 4) Q.E.D. ribozymes blocked rendered ineffectual |
I can neither confirm nor deny ever having E.D.'d, but I'm willing to try it if it will help the cause, and someone can provide me with step by step instructions and the necessary ribozymes. As long as it is no harder than Sea-Monkeys, I should have or be able to improvise any laboratory equipment needed (tupperware, microwave, blender, power tools, hybrid bicycle, fire, nails, ziplock bags, Dr. Pepper, batteries). Let me know if I have left anything important off the list - I might have it. |
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anniid
Lonely Fan
Joined: 08 Dec 2006
Posts: 241
Location: A snowflake
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| Posted: Wed Jul 11, 2007 10:52 pm Post subject: Re: Look at us. we're so cool... |
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| kellylen wrote: | | SivartAlappes wrote: | | anniid wrote: | See!?
You should have posted that paper sooner... within 2-3 hours we had a solution. (It's correctness is um... relative...)
Alright. Check our solution and give us another puzzle!!!
Come on... you know you want to, Spencer. |
1 hour and 41 minutes, actually. |
actually i think its a lot less than that |
well his first post was at 7:30--something.
then we finished at 9:17
_________________
One day you'll know who I am. On that day, so will everyone else.
Acting president of the Jonas is Sexy Fan Club!
Member of the Sarah Fan Club and the Daniel-Sarah Romance Promotion Force. |
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thoughtssopoetic
Enthusiastic Fan
Joined: 24 Jun 2007
Posts: 429
Location: at my computer. refreshing this page.
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| Posted: Wed Jul 11, 2007 11:19 pm Post subject: Re: Look at us. we're so cool... |
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| anniid wrote: | | kellylen wrote: | | SivartAlappes wrote: | | anniid wrote: | See!?
You should have posted that paper sooner... within 2-3 hours we had a solution. (It's correctness is um... relative...)
Alright. Check our solution and give us another puzzle!!!
Come on... you know you want to, Spencer. |
1 hour and 41 minutes, actually. |
actually i think its a lot less than that |
well his first post was at 7:30--something.
then we finished at 9:17 |
I am now cursing the fact that I have night class from 6-9:30
gah.
_________________
my real name is kasienka, just call me kait
founder of the "WNSASUANOTF" homies, along with Charles and Les.
member of the spencer fan club and sarah fan club.
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I'm mad at David Yates and Michael Goldenberg. That was NOT how Sirius died. |
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BlackCatonMars
Casual Observer
Joined: 02 May 2007
Posts: 33
Location: Rochester, NY
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| Posted: Thu Jul 12, 2007 2:14 am Post subject: Re: Look at us. we're so cool... |
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| thoughtssopoetic wrote: |
I am now cursing the fact that I have night class from 6-9:30
gah. |
I was eating dinner and then watching the movie Sneakers and didn't get back online until I was of no use...and I've been waiting for weeks for a chance to help out! Oh well. |
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marlasinger
Devoted Fan
Joined: 27 Feb 2007
Posts: 736
Location: The 8th Dimension
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| Posted: Thu Jul 12, 2007 7:54 am Post subject: |
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wooooooord! Kelly we posted that theory that i was talking about last night here http://www.lonelygirl15.com/forum/viewtopic.php?t=12203. Take a look and tell me what you think - things to remember - no double stranded rna (rNAi), just complementary and active strands. Someone's already mentioned that it might be science fiction.
_________________
my love tastes a lot like tofu.
The Bree Solution.
http://one.revver.com/watch/330795
"Also... im in ur canons... supporting all ur marlas."
-AutoPilate |
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